What fresh hell is THIS now? - Patrick Lauke
mailto
could be parsed and a different announcement made.
[Andrea Skeries, a11y] ZoomText has many options to enlarge everything and change colors on the screen. There are tools to make it easier for people with low vision to see where they are by providing larger cursors and bold styling for things that have keyboard focus. It also has a screen reader built in that can work a little differently than the rest. Using the "Speak It" tool, you highlight the text and it will read that.
One bug I've ran into with it is when text is "hidden" on the page or text is temporarily hidden with show/hide triggers. The hidden text is still in the HTML and if you use "inspect element" browser tool you can see where it would be. If it is under other text that you try to highlight it could instead read the text that is hidden instead if it comes in the markup before what you're actually highlighting. It's hard to explain, but I do think you should test with it to catch these odd cases. You can get the free trial to experiment with it: http://www.aisquared.com/products/zoomtext/
Window-Eyes screen reader is free of charge to people with a licensed version of Office 2010 or later so definitely worth testing as well.